Progesterone Is Important for Transgender Women's Therapy

[Sometimes Chrissie]

https://academic.oup.com/jcem/article/104/4/1181/5270376

 

The main takeaways from this study:

 

Progesterone blocks androgens. 

 

Progesterone speeds up transition.

 

Progesterone makes transition safer.

[Billie38]

Thanks for posting this article.  I was thinking about asking my doctor if I should lower my Evamist estradiol, progesterone and Bicalutamide dosages since I've been on them 5 years and all of the changes I expect are done.

 

If estradiol levels drop too low I get hot flashes (ugh!) so I don't know if going down from XX pg/ml to XX is practical.

[Charlize]

While this is an interesting article my endocrinologist and cardiologist both cite studies where progesterone can cause increased risk of coronary issues including death.  Both believe that topical E is the safest path.  While it may have taken longer as a person with severe cardiac issues i prefer life to speed.  An orchiectomy has taken care of the T and topical E in the form of Evamist has worked it's wonder.  Best of all i'm still here to enjoy my life.

 

Hugs,

 

Charlize

[Mmindy]

3 hours ago, Charlize said:

Best of all i'm still here to enjoy my life.

Yes, it is good to have you around. 
 

Enjoy 

[Willow]

Very good information.  I take progesterone, and inject estradiol and for three more days spironolactone.  When we discussed medication post orchidectomy my endocrinologist said he would want to switch to a patch.  We didn’t discuss progesterone yet.