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  1. I hope some here can provide a more in-depth explanation than my endo did for why my progesterone level tested so high. I don’t smoke, drink or do drugs; I’m in very good health. But this month was the first time that I had asked to have progesterone tested. The testes produce most of the progesterone in cis men. But I’m 10 years post-op and have been on estradiol valerate injections twice monthly long before and ever since. So I was shocked when the blood levels showed it at 13 ng. My endo said that the adrenals are evidently producing enough progesterone to balance my exogenous estro
  2. Hi, Has anyone else had negative consequences of adding Prometrium to injected Estradiol and Spironalactone? I added ...... of micronized progesterone, then went up to...... I slept a bit better at first, but that was about it. After a while I got more and more irritable and irrational and unable to handle stress, along with increased pain from old repetetive motion injuries and insomnia. I also feel like my facial hair grew more quickly and thicker. My breasts did get a bit rounder/fuller, and the areolas are about twice the diameter they were. Of course I have no way to tell if it
  3. While I was in the hospital recently (I'm better now), a scan was done on my right leg and they actually found a blood clot in one of the superficial veins. The doctor seems to believe that it may have been caused by the progesterone I've been taking. He said it wasn't DVT but it had potential to eventually become that. He seemed to rule out my job where I spend most of my time sitting, although that also could lead to blood clots, and he also seemed to rule out those 2 weeks when I was taking oral estrogen. So, I'm now on a blood thinner for 3 months and I think I'll be talking to my end
  4. I heard something about blood clots in relationship to smoking and estrogen/progesterone therapy. Can anybody explain this further? Or perhaps a good web page on the topic? I'm having a hard time locating a lot of information. Nova

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