Jump to content
  • Welcome to the TransPulse Forums!

    We offer a safe, inclusive community for transgender and gender non-conforming folks, as well as their loved ones, to find support and information.  Join today!

Struggling With Spironolactone/Diuresis


SunnyKay

Recommended Posts

Hello Everyone! I started HRT on October 26 of this year and I couldn't be happier! YAY!!! So I'm well into my second full week of hormones, but I find I'm struggling with the diuretic effects of spironolactone. I'm 38, and 144 lbs normally but within 24 hours of taking my first dose(s), I experienced 4lbs of water loss, and since have gained back half that at best, usually hovering around 140. An uncomfortable weight to be for me at 5'7" Last night I ended up I the ER due to severe pain while urinating, cloudy urine, and blood in urine. OMG!! UTI's are SO, SO, SO PAINFUL! To keep it short, the doctor said I had a raging UTI, and was super dehydrated. I really have been chugging water, but maybe I have no conception of how much I need to drink to offset spironolactones diuretic effects. Taking a day off this stuff today.  And BTW, caffeine and alcohol are dead to me until I can manage this better. The best possible health while on HRT is my complete focus right now.

 

So I'm asking if anyone has advice for dealing with this. Maybe I have no idea of the quantity of fluids I need right now.  It would be super helpful if someone who has dealt with this could share their experience. Grateful for any replies and advice! 

 

Fuzzy Hugs,

 

Sunny 

Link to comment
  • Admin

My big guess is that the UTI was starting before you got onto the Spiro, but you do have to be careful about how much water you drink and what the Potassium levels are while on it.  Two 8 oz glasses of water at meal time, plus non-sports drink stuff as you want it. A rule of thumb my doctor gave me, was input and output should be about equal.  My doctor actually had me do a 48 hour test using a special toilet insert while I was home to measure the output. Do be careful about Potassium in such things as sports drinks, since your body does not get rid of the potassium as fast as it used to, and too much can affect other organs and make you feel weaker.  I am post op and get UTI's a couple of times a year due to my new plumbing, but I had them before as well.  Just be sure to keep your lab appointments and take other drugs on schedule.  Knocking off the drinking and caffeine will help generally in so many ways.  It will be several months before you get completely used to the HRT.  I have 9 years if experience with the stuff and it still pull surprises on me, and not all perfect and fine.

Link to comment
  • Admin

Hi, Sunny.  Sorry to hear about the UTI and your other effects from Spiro.  Obviously, I'm not a doctor, so I won't be offering any specific medical advice.  That said, I suggest waiting until your UTI is gone, and go back to whichever doctor prescribed the Spiro and discuss it with them.  They may be able to change your dosage, or offer an alternative, such as Finesteride.  Spiro is not the only way to go to get results.

 

I hope you feel better.

 

Carolyn Marie

Link to comment

Hi, Sunny...

 

I also had difficulty with spironolactone (although I can no longer recall what they were).  I was switched to finasteride and have had no issues at all with that.

Link to comment
  • Forum Moderator

Hello Sunny, Yes the Spiro will dehydrate you if are not careful about keeping a positive fluid intake.  That and as mentioned your Potassium levels can go into the bad range too.  I used to drink a gallon of water a day.  That may seem like a lot but once you get used to it, its fine.  I also get leg cramps if I don't stay hydrated.  Now that I'm just on E, I still drink a lot of water each day.  As to your weight, I am taller than you but have been at 140 for a long time so I wouldn't worry about that too much except to say listen to you body.  It will tell you what is working and what isn't.  My weight fluctuated a little at the start of HRT but then settled back to my norm.  As suggested, you can talk to your doctor about an alternative to the Spiro and see what they say.  I'm glad you went to the hospital and got the UTI looked into.  They are no fun.   <Hugs>

 

Jani   

Link to comment

Thank you all so much for your quick replies and support. This group is really amazing! It really helps to get feedback from individuals who gave been down this path before....

 

I'm up and about now, and drinking soooo much water. I feel better already! But, I will stay away from sports drinks, since I don't need the extra potassium.....

 

OMG Vicky! You must know how painful these things are. Not fun!

 

Thank you all again!

Sunny Kay

Link to comment
  • Admin
2 hours ago, SunnyKay said:

OMG Vicky! You must know how painful these things are. Not fun!

 

Not so much pain all the time, but when I gotta go, I really really gotta gotta go or there have been wet underpants.  I came down with one at a convention in Atlanta GA and was in ATL airport getting ready to come home cross country and the urge hit in the TSA Screening line.  Thank heaven I had a spare pair of undies in my carry-on case which got used there in the airport.  I was making one trip to the head on board the plane every 1/2 hour for 4 hours and a bit more.  UTI's are NOT FUN at all!!

Link to comment

Carolyne and Kenna, thanks for the heads up on finasteride......If Spiro continues to not cooperate I will bring this up with the Endo. I'll look into it a little more to see what it's liver tox profile is as well....

 

Sunny

Link to comment
  • Forum Moderator

I made a point of looking up the potassium levels of certain foods and modified my diet a bit.  i got into drinking an amazing amount of unsweetened green tea either hot or as iced tea.  Even though surgery makes the need for a blocker no longer necessary i continue to drink more than i ever did before but also enjoy coffee in the morning.  One thing to watch for is cramping.  that is another sign that your not drinking enough and have high potassium.  I had leg cramps on occasion that were pretty brutal.

 

Hugs,

 

Charlize

Link to comment

Thats a good idea. I'm in the process of realizing I need to do some housecleaning with my diet, and lifestyle to make sure it works with my HRT. But seriously.....I can't even drink 2 cups of green tea in a day though without it drying me out, sometimes even forcing me to take out my contacts! I think I'm going to stick with LOTS of water right now.

 

And yes, I take my water straight.....No chaser......:blink:

Link to comment
  • Forum Moderator
10 hours ago, SunnyKay said:

water straight.....No chaser

Yes This^  I used to drink a lot of seltzer water, and I still enjoy it but the vast majority of my drinking water is plain old filtered tap water.

 

Jani

 

Link to comment
16 minutes ago, Jani423 said:

the vast majority of my drinking water is plain old filtered tap water.

 

 

Aren't you concerned about hydric acid (dihydrogen monoxide)?

Link to comment
Guest Rachel Gia

I dunno but I always thought finasteride is more associated with correcting hair loss.

I brought up my issues with spiro last week with my transition doctor and she said that there were other blockers that I could go to.

I had corrected the problem with diet and so I stayed on spiro.

Water is so important and like was said above potassium is really something to look act as a no fly zone.

Bananas I just don't eat and will stay away from dates now because of it.

There is a boat load of bad stuff out there in things like maltitol which is now used in a lot of things as sweetener but it also is a constipator.

Water and diet and let your trans doctor figure it out.

Link to comment
2 hours ago, Cerise said:

I dunno but I always thought finasteride is more associated with correcting hair loss.

 

 

That's true, but my prescription states that it's for prostate enlargement (which I don't have).

Link to comment

Ok, so since I posted last I've been drinking SOOOOO much more water, and my weight has now gone back up closer to where it should have been. Back up to 143 ish instead of 140ish. AND....I feel much better overall. I am surprised how much water it takes to rehydrate! Back to the full dose of Spirolactone, and handling it in fine form. Still, it's a very serious drug with serious effects and I have alot more respect for it now. Going to the bathroom so much is an inconvenience at times, but a completely acceptable trade-off for my goals.

 

Link to comment
Guest Rachel Gia

Hi again, one thing I noticed is that you basically just started spiro and I had a few problems at the beginning with it that I posted under Spiro Giro.

I basically had clashes with a few things that I was ingesting but with a little help from this forum and personally nailing down what was clashing with the spiro I kept on it.

My first issues was a general lightheaded feeling after taking it and sometimes feeling a slight loss of strength.

All this has gone away and most noticeable reaction was when I forgot to take it one day before going to work.

Basically it is a blood pressure med that happens to block T and thus it is used for that and other medical issues.

Your right ....it is a serious drug!

I have been taking it for 14 months and I would say it is pretty much transparent in side effects now.

i have had the water issues and when I get up in the middle of the night to go I drink more before going back to bed to keep hydrated perhaps out of fear of getting blocked up but also out of respect for the unwanted possibility of gallstones (shudder).

One other thing is sometimes there are shortages of the drug , at least there are in Canada.

Link to comment
  • Forum Moderator

Sunny, I'm glad to hear you're finding balance now.  Keep up with the water intake!
 

Jani

Link to comment
  • Forum Moderator

I got into the habit of drinking a great deal when i was taking Spiro.  That has stuck with me even though after an orchi T is no longer a problem.  I've found i still have to get up once every night.  Ugh..... that may also be of my getting a bit older......double ugh.  Anyway i ended up having to take a pill to lower my water intake as my body had become used to the effects of Spiro and i was retaining water and my ankles and legs were swelling.

This brings to mind one of the reasons this site has been so stringent in not allowing dosages and plans for self medication to be posted.  As both sunny and Cerise have noted this is a serious drug and can cause major health problems.  Any of us who travel this path have to remember that and get the best medical care that we can.

 

Hugs,

 

Charlize

 

Link to comment
  • 4 weeks later...

Just a little update...I've learned that splitting the dose by 2-3 hours was super helpful and further reduced my body load and water loss. So now instead of taking 2 pills at 9:30, I take one when I wake up and one after I get to work. I feel much better and my weight is back to where it should be once again. Just posting this update in hopes it will help someone who is wrestling with spiro as i did.

 

Blue Skies and Sunshine, 

 

Sunny Kay

Link to comment
  • 10 months later...
  • Forum Moderator

I don't remember those symptoms.  Please call your doctor and ask for advice.  Giving medical advice here is beyond anyone's ability.  Even a doctor would not comment without knowing you, your history and circumstances.  Make an appointment!

Take care of yourself.

 

Hugs,

 

Charlize

Link to comment

Thanks for reply was not asking for advice I should have typed ina bettter way sorry.   Spironolactone  stoped make my heart beat faster but did  give me soreness in chest after a some time it stoped  every thing doing great I have been under doctor care for 5 yrs things are doing great

Link to comment
  • Forum Moderator

That sounds great.  Thanks for the clarification.

 

Hugs,

 

Charlize

Link to comment

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Who's Online   4 Members, 0 Anonymous, 90 Guests (See full list)

    • Abigail Genevieve
    • Ashley0616
    • VickySGV
    • Avra
  • Recently Browsing   0 members

    • No registered users viewing this page.
  • Forum Statistics

    • Total Topics
      80.6k
    • Total Posts
      767.9k
  • Member Statistics

    • Total Members
      12,014
    • Most Online
      8,356

    Quillian
    Newest Member
    Quillian
    Joined
  • Today's Birthdays

    1. l.demiurge
      l.demiurge
  • Posts

    • Ashley0616
    • Ashley0616
      – According to a recent survey, the most popular name for a dog is Max. Other popular names include Molly, Sam, Zach, and Maggie.
    • Ashley0616
    • Ashley0616
      Either new environment/ not potty trained
    • Abigail Genevieve
      Bob was on his way home from the dojo and he "just happened" to driver by her place. It was 10:30.  Her light was still on.  He knew exactly where she was sitting.  He saw her in his mind.   A fierce wave of desire that took his breath away suddenly showed up. All he had to do was stop, get out of the car, walk to the door and knock.  She would answer, glad to see him.  She would know why he was there and what he wanted. She would invite him in, maybe get him something to drink, disappear for a moment and return in "something more comfortable."  She would lead him back. Oh, joy.   And never, ever speak to him again afterwards.  Or she would not let him in but be angry about it.  In no way, emotionally, physically, mentally or spiritually, was she ready for this, and he knew it, if he was honest with himself, and she knew he knew it.  She would look upon it as another assault and their relationship would be irretrievably broken.  He would have to leave town. It would devastate her. It would devastate him.    He fought himself.  He was frozen to his seat as his reason and his body fought. He was twenty four years old, a full-blooded male with normal desires; he had just worked out and he was ready.  All he had to do now was open the car door. No one would know. He held his hands, one in the other, to keep one from moving, against his reason and will, to open that door.  He did not want to be a slave of his desires.   He looked across the street.  Mrs. McCarthy, sister of his landlord, was peeking though her window.  She knew his car.  Everyone in town would know by noon the next day if he got out of the car.  Taylor did not need that, either, and she would know, if he came to the door now, what a selfish thing it would be: in his own eyes, in the eyes of Taylor, in the eyes of the town, and worst of all, in the eyes of God.   He sat there a moment longer.  He was, as he reflected, entering into her sufferings in a small way that she would be made whole, healthy and happy: what he wanted more than anything.  But this hurt.  Why had all this come on her?  He asked God again, but there was only silence. He drove home in that silence. He chided himself for even going on her street and for driving on it other nights.  He would stop that, he told himself.   ------------------------------------------   The next morning Taylor went out to her car to go to work.  Mrs. McCarthy met her before she got to it. "I thought you were going to get lucky last night, dearie," she said. Taylor was puzzled. "Why, what do you mean?" "That young fellow - you know, Bob - he's been driving around here, going up and down the street some nights, not stopping.  Well, last night he parked and sat in his car for a while.   I think he was staring at your window.  I think he was trying to get up the courage to knock on the door. I was rooting for him.   But then he drove away.  Faint heart never won fair lady, as they say. What a shame. You two are a lovely couple.  Well, have a good day!" "Thank you, Mrs. McCarthy."  Taylor knew Bob extremely well and knew what had been going through his mind.  She was more than grateful he had not gotten out of the car. Better for him, better for her, better for everybody.  Surgery "down there" sooner than later.  This was driving the poor boy crazy. It was driving her crazy, too.  But she had a lot to work through. Surgery "up here" she said, pointing to her head.  She woke up her therapist on the way to work.  They were still talking when she pulled into her designated parking spot.  That was a perk that had happened yesterday.  She took a deep breath and headed into work. It would be another wild day.
    • Ashley0616
      bittersweet: especially : pleasure accompanied by suffering or regret
    • Abigail Genevieve
      I'm thinking about some interactions yesterday I did, while presenting as male but acting as female, that were far better than I did when I was presenting as male and acting as male.  #girlunderhood. I do a crappy job at acting as male and I am giving it up.  I am not talking about feminine gestures or presentation but just relating as a woman.  People don't realize I am doing it but it is a whole lot easier to do.   You don't just put on a dress and BOOM you are a girl.  You are a girl and you put on a dress.  Or not. Whether I am in jeans or a skirt (I wish, wife would have lots to say) I am a girl.  I don't need $250 in makeup and heels and hose and all that.  I don't need surgery. Honey, I have arrived.  Now I have to work out how that best works in my life, causing the minimal damage and creating the maximum good, but I have more working room.   Oh, and I am still pissed off at everyone and everything. #Contradictory.
    • awkward-yet-sweet
      @Willow it is certainly possible that my husband planned it. Placing me in the path of an opportunity....he certainly does things like that. GF has done some work for the company as an outside consultant, so I'm sure the company owner knows what potential resources are around.    It could also have just happened randomly. He has taken me to work with him before, just because he likes to have me around. I remember one time that I fell asleep with my head in his lap, and he held a meeting with his subordinates without waking me and making me move.  The company culture is family oriented and relaxed.
    • Abigail Genevieve
      The photo is great.  Software is phenomenal but it also is sort of a promise of things to come. Years ago this sort of thing took a photographer and Photoshop and all sorts of things and you would say, "I can look like THIS??"   Me, I am a duck.  That's from my driver's license.  Just kidding.
    • MaeBe
      I lucked into that picture. I took like 10 before that, which appropriately make me look like a donkey. ;)   Thank you so much for the compliment!
    • Mmindy
      You're welcome Sally,   Hugs,   Mindy🌈🐛🏳️‍⚧️🦋
    • Mmindy
      This is a great analogy. The statement is true as it relates to the tree. The analogy fits because we as a LGBTQIA community are stronger when we stand together. It also work here on Transgender Pulse Forums. The support I feel from so many others has made me comfortable with my stance, because I'm in a beautiful forest of friends. So when I'm out alone and confronted. I can respond and act like the single tree in the field, surviving whatever comes my way. My roots reach back and communicate with others like me.    Standing Strong,   Mindy🌈🐛🏳️‍⚧️🦋
    • Ashley0616
    • Ashley0616
    • Sally Stone
      Mindy, that would be so awesome of you.  Please make the edit for me, and thank you so much!
  • Upcoming Events

Contact TransPulse

TransPulse can be contacted in the following ways:

Email: Click Here.

To report an error on this page.

Legal

Your use of this site is subject to the following rules and policies, whether you have read them or not.

Terms of Use
Privacy Policy
DMCA Policy
Community Rules

Hosting

Upstream hosting for TransPulse provided by QnEZ.

Sponsorship

Special consideration for TransPulse is kindly provided by The Breast Form Store.
×
×
  • Create New...