Progesterone is it helpful

[Guest Emily Ray]

I went to a transgender health conference this past weekend and one of the clinic's I attended was about HRT for transwomen. I learned somethings about progesterone that has convinced me I need to take it.

The dominance of estrogen in menopausal women can cause insomnia and depression. Adrenal fatigue, and lower cortisol levels can also occur. I am going to ask for bloodwork to check for these issues because the also can cause insomnia and depression.

What does this have to do with progesterone? Well it is the treatment for any of the above conditions. E and P work together to produce balance. Too much of one or the other can cause problems. What does E do with P? It upregulates the receptors or causes more of them to form on the cell membrane. What does P do with E? It increases the sensitivity of the cells to E.

I don't know why I didn't research these hormones together in the past, but if you do a google search with both terms you will get a good picture of how these two can effect your mood and other issues. You will than be able to have an educated conversation with your Dr.

Huggs

Emily

[Guest Donna Jean]

.

I've been on P for almost 2 years and the only thing that I can attest to is that it makes me an emotional mess for 10 days out of the month...

A couple of days ago I was with my new doctor (a post-op trans woman herself) and she told me to go ahead and stop them....there has been no benefit....

I was first on Prometrium and then Medproxy....

[Guest Emily Ray]

Did you experience a difference on the different types. From what I have read cycling is not necessary. Did you ever try to stay on it for the whole month. I guess everyone is different and that needs to be recognized.

Huggs

Emily

[~Nova~]

I went to my ob-gyn to get my checkup. She did her normal thing and felt my breasts, although growing, needed help to fill in. She told the Prometrium will not make them bigger, but fuller.

I've only been on them for about a week or so, but the one thing I noticed is the flashes about an hour after I take it. Wow! One second comfy, then I'm sweating, then I'm cold, them I'm sweating. I love it!

I've been having a pretty good couple weeks so I don't know if it's done anything in the psych dept. I've seen no breast growth yet.:-(.

Autumn

[Guest Donna Jean]

Did you experience a difference on the different types. From what I have read cycling is not necessary. Did you ever try to stay on it for the whole month. I guess everyone is different and that needs to be recognized.

Huggs

Emily

On the Prometrium for over a year and took it all 30 days of every month....

The second year on Medproxy I've taken the first 10 days of the month....

I was crazy on both of them!

Dee Jay

[Guest Emily Ray]

I was on medroxyprogesterone in the very beginning and I had hotflashes as well when I cycled it. But, if you look at the side effects of E and P side by side it is E that is responsible for the hotflashes. What I gather from this is that the one effects how the other interacts in the body.

If I go back on it I want to try prometrium and not cycle it. It may be helpful to my mood and help me sleep so I can get off of the Ambien I am taking. If it works out oraly I will ask for it in my injections. Fewer pills and less work on the liver.

Another thing that I learned in the clinic is that while sex hormones have very little drug interaction they do stake up space in the liver. The liver can only proccess so much and when it is maxed out that's it. That means that if it is being taxed with the processing of one substance another one can't be proccesed. This of course is happening on a molecular level. Some enzymes though will have an affinity for one type of reaction over another.

It all gets very complicated very fast and is why a Dr is needed. This does not mean though that they are always aware of every issue that needs to be watched.

Huggs

Emily

[Guest Donna Jean]

If I go back on it I want to try prometrium and not cycle it. It may be helpful to my mood and help me sleep so I can get off of the Ambien I am taking. If it works out oraly I will ask for it in my injections. Fewer pills and less work on the liver.

Huggs

Emily

The biggest difference is that Prometrium is made naturally from extracts of yams.....

Medproxy is manufactured......

Dee Jay

Huggs

[Drea]

I been on several regimens. It all is mostly hocus pocus in my opinion.

What one finds researching has little meaning unless one is able to look at it critically and to do so in a sensible fashion requires the experience the professionals have. Otherwise one can read just about anything they want out of the available information.

[Guest Orva26]

I have a question.

What type of research has been on this? Specifically double hormone HrT for transwoman?

From someone I know I got the impression that there really hasn't been real clinical validation of a benefit only inferences.

[Drea]

From someone I know I got the impression that there really hasn't been real clinical validation of a benefit only inferences.

Other than the basic "hormones are an effective treatment for trans" type of conclusions, to my knowlege there is nothing that amounts to clinical trials of different regimens in trans folk that measured the relitive effectivness.